Dr. Louise Lincoln was a colleague and friend of Crystal Frost, the villainess known as Killer Frost. After Frost died, she decided to repeat the experiment as a last respect to her former mentor, and became the new Killer Frost. She became just as ruthless as her predecessor and began her own personal vendetta against Firestorm, who she blamed for Frost's death. She briefly served as a member of the Suicide Squad and sold her soul to Neron for more power.